Ishita Shah, CEO of Matrubials Inc. – Building Milk-Inspired Therapies for Infectious Diseases | TiE Women’s Program Silicon Valley 2025
At the TiE Women’s Program – Silicon Valley, we highlight women founders who are reshaping critical sectors such as health, biotech, and preventive care. Ishita Shah, CEO of Matrubials Inc., is leading a scientific and clinical shift — drawing from nature to develop breakthrough therapies for infectious diseases.
The Problem
Antimicrobial resistance is a global healthcare threat and infectious diseases continue to disproportionately affect women and underserved communities.
Current treatment approaches can be:
- Limited in effectiveness
- Harsh on the microbiome
- Prone to resistance development
Patients deserve therapies that are effective, targeted, and gentle — without compromising safety or accessibility.
Matrubials’ Solution
Matrubials develops milk-inspired, nature-derived therapies designed to treat infectious diseases with higher precision and less disruption to the body’s natural defenses.
Their first applications target:
- Women’s health
- All-gender skin health
By mimicking the antimicrobial mechanisms found in nature — particularly in human milk — Matrubials is designing treatments that support both prevention and healing, while protecting the microbiome.
This is healthcare that works with the body, not against it.
Why It Matters
Traditional antimicrobial treatments often:
- Over-target the body’s microbiome
- Fuel antimicrobial resistance
- Introduce side effects that limit use and adherence
By leveraging nature-inspired science, Matrubials is building therapies that are:
- Targeted
- Microbiome-preserving
- Clinically effective
- Accessible and scalable
This approach has the potential to redefine preventive and therapeutic care worldwide.
About the Founder

Dr. Ishita Shah blends deep scientific expertise with mission-driven leadership.
Her work is grounded in:
- Biomedical research
- Clinical translation
- A commitment to women’s health equity
She is building Matrubials with a clear vision: to make scientifically advanced, nature-aligned therapies accessible to all who need them.
This is the kind of founder the TiE Women’s Program is proud to champion.
Powered by TiE Women – Silicon Valley
The TiE Women’s Program champions women founders through:
- Expert-led masterclasses
- 1:1 mentorship
- Access to investors and industry networks
- Pitch opportunities
When women lead innovation, healthcare moves forward.