đź’ˇ The A to Z of Fundraising: Unpacking Investor Secrets from TiE Silicon Valley’s Investors Panel

Welcome to the heart of Silicon Valley! Last week, the TiE Silicon Valley University Mentors Program hosted an electrifying webinar, “A to Z of Fundraising,” featuring an incredible panel of early-stage Venture Capitalists. The event, driven by the core Silicon Valley mindset to “pay it forward,” offered student founders and early-stage entrepreneurs an unvarnished look into what makes a pitch stand out—and what makes a VC say no.

The diverse panel included: Akash Pai, Angel Investor & Board Member, NuFund Venture Group, Alperen Ozalp, Managing Principal, Alpine Rock Capital, Alicia Castillo Holley, GP & Founder, Wealthing VC Fund
Zoe Samuel, Venture Partner, Starshot Capital

Here are the key takeaways from our esteemed panel on what they look for and, more importantly, what turns them off.


đź’° Meet the Investors: Diverse Funds, Focused Strategies

Each VC brought a unique focus to the table, underscoring that founders must always tailor their pitch to the investor’s specific mandate.

VC & FundFocus/SectorTypical First Check SizeNotes
Akash Pai (New Fund)Area agnostic, but often high-quality biotech, digital healthcare, and hard tech (Seed-level deals).$300K – $500K (Seed); $100K (New Pre-Seed Fund)Run like a fund, not an angel network. Commits to a 6-week decision timeline post-pitch.
Alicia Castillo Holley (Investment Club & Fund)Sector agnostic (with a few exceptions: gambling, alcohol, drugs, animal-based products, platforms).$50K – $400K (Club entry); $1M – $6M (Fund follow-on)Entry is always through the Investment Club first for at least a year. Due diligence takes about one month.
Alp Ozalp (Life Science Angels)Life Sciences and Healthcare (therapeutics, biotech, medical devices, digital health, healthcare AI).$100K – $750K (Syndicated for larger round total).Focuses on Seed and Series A, with some Pre-Seed and Series B. Try to respond in 6-8 weeks.
Zoe Samuel (Starshot Capital)Climate-only (Built environment, industry, agriculture/food systems).$500K – $1.5M (First check)Invests Pre-Seed through Series A. Stresses that their capital is not concessionary—they expect conventional VC returns (100X potential).

âś… What VCs Look For: The Key to a Killer Pitch

When asked for the single most important thing they look for in a pitch, the panelists focused overwhelmingly on the founder and the quality of their thinking:


❌ The Ultimate Turn-Offs: What Makes an Investor Tune Out

If the above points make a pitch, these actions guarantee a swift end to the conversation:


Are you ready to pitch? The consensus from TiE Silicon Valley University Program Webinar with the Investors’ panel is clear: great ideas are necessary, but mature, financially literate, coachable, and passionately authentic founders are the ones who get the check.